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Available clinical data indicate that adding cagrilintide to semaglutide does not substantially increase nausea or vomiting compared with semaglutide alone ( Management of GLP-1 induced nausea and vomiting The cornerstone of preventing nausea and vomiting with GLP-1based therapy is understanding that gastrointestinal adverse effects are primarily dose related rather than drug specific

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doi: 10.2337/dc06-1277

Since Retatrutide may be able to reduce liver fat in people with obesity, it could also prevent the progression of NAFLD (2)